An approximate estimate of the ion-activity product of calcium oxalate in rat urine
An approximate estimate of the ion-activity product of calcium oxalate in rat urine
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大鼠尿液中草酸钙离子活度积的近似估计
DOI：
10.1007/s00240-003-0363-9
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发表时间：
2003
影响因子：
--
通讯作者：
Ita Pfeferman Heilberg
中科院分区：
文献类型：
--
作者：
H. Tiselius;Renato Ribeiro Nogueira Ferraz;Ita Pfeferman Heilberg
本报告的目的是对大鼠尿中草酸钙的离子活度积(APCaOx)进行简化的近似估计。使用EQUIL2程序通过迭代计算机化近似来评估每个尿变量的相对影响。从文献和实验数据中选择一个基本的尿液成分。对APCaOx值影响最大的是尿钙、草酸、柠檬酸、镁和尿量。根据这些计算，得出了AP(CaOx)指数RAT.对于24小时的尿样，因子A取值4067，因子F应设置为0.015。结论。推导了大鼠尿中APCaOx值的简化近似估计值。AP(CaOx)指数与APCaOx之间有相当好的一致性，由公式2得出(r=0.890)，只要其他尿变量与基本成分的偏差不是很大。
The objective of this report was to derive a simplified approximate estimate of the ion-activity product of calcium oxalate (APCaOx) in rat urine. The relative effect of each urine variable was assessed by means of iterative computerised approximation with the EQUIL2 program. A basic urine composition was chosen from literature and experimental data. The most pronounced influence on APCaOxwas recorded for urinary calcium, oxalate, citrate, magnesium and volume. Based on these calculations, an AP(CaOx) indexRATwas formulated:. For a 24-h urine sample, factor A takes the value 4067 and factor F should be set to 0.015. Conclusion. A simplified approximate estimate of APCaOxwas derived for rat urine. There was a reasonably good correspondence between AP(CaOx) indexRATand APCaOx, as derived from EQUIL2 (r=0.890), provided the other urine variables do not deviate very much from that in the basic composition.