Intensity-modulated radiotherapy with a belly board for rectal cancer
Intensity-modulated radiotherapy with a belly board for rectal cancer
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DOI：
10.1007/s00384-006-0166-x
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发表时间：
2007-04-01
影响因子：
2.8
通讯作者：
Cho, Kwan Ho
中科院分区：
文献类型：
--
作者：
Kim, Joo Young;Kim, Dae Yong;Cho, Kwan Ho
背景与目的调强放射治疗（IMRT）技术可以减少直肠癌患者受照射的小肠体积，但联合使用IMRT和腹板治疗直肠癌患者尚未见报道。本研究的目的是确定额外使用腹板是否会减少直肠癌患者仅使用 IMRT 观察到的受照射小肠体积。 材料和方法 20 名计划接受直肠癌术前放疗的患者接受了两组 CT 扫描，无论是否使用腹板。使用 6-MV 光子束和七个等距场进行 IMRT 规划。以 10% 的间隔分析膀胱、小肠和计划目标体积 (PTV) 的处方剂量 10% 至 100% 之间的剂量。使用 Wilcoxon 符号秩检验对数据进行分析。结果 接受带腹板 IMRT 的患者与不带腹板的 IMRT 患者在小肠总体积、膀胱和 PTV 方面没有显着差异（分别为 p=0.571、p=0.841 和 p=0.870）。统计分析显示，使用腹板的照射小肠体积比不使用腹板的小肠体积小（20-100%剂量水平下p<0.05），照射小肠体积的平均相对减少量为37.8+/-32.8%。结论使用腹板的IMRT在减少照射小肠体积方面比单独IMRT更有效。这些研究结果表明，使用腹板联合 IMRT 可能会减少术前放疗中的小肠并发症。
Background and aim Intensity-modulated radiotherapy (IMRT) techniques can reduce the irradiated small bowel volume in rectal cancer patients, but combined use of IMRT and a belly board is yet to be reported on for rectal cancer patients. The aim of this study was to determine whether additional use of a belly board reduced the irradiated small bowel volume observed using IMRT alone in rectal cancer patients.Materials and methods Twenty patients scheduled to receive preoperative radiotherapy for rectal cancer underwent two series of CT scans, with and without a belly board. IMRT planning was performed using 6-MV photon beams and seven equispaced fields. The bladder, small bowel, and planning target volume (PTV) were analyzed for doses between 10% and 100% of the prescribed dose at 10% intervals. Data were analyzed using Wilcoxon signed rank tests.Results There were no significant differences between patients undergoing IMRT with a belly board and those without a belly board in terms of total small bowel volumes, bladder, and PTV (p=0.571, p=0.841, and p=0.870, respectively). Statistical analysis showed that the irradiated small bowel volume with a belly board was smaller than that without a belly board (p < 0.05 at 20-100% dose levels), with the mean relative reduction in the irradiated small bowel volume being 37.8 +/- 32.8%.Conclusion IMRT with a belly board is more effective than IMRT alone in reducing the irradiated small bowel volume. These findings suggest that the use of a belly board with IMRT may reduce small bowel complications in preoperative radiotherapy.