Senescent macrophages: A new "old" player in lung cancer development.
Senescent macrophages: A new "old" player in lung cancer development.
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DOI:
10.1016/j.ccell.2023.05.008
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发表时间:
2023-07-10
期刊:
影响因子:
50.3
通讯作者:
Ruscetti, Marcus
中科院分区:
文献类型:
--
作者:
Zhou, Lin;Ruscetti, Marcus
Senescent cells accumulate following oncogene induction, but their role in transformation remains unclear. Prieto et al. and Haston et al. found that senescent cells in premalignant lung lesions are mainly macrophages that promote lung tumorigenesis, and removing them through senolytic approaches can prevent malignant progression.
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DOI:
10.1073/pnas.1818313116
发表时间:
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