Association between dementia and mortality in the elderly patients undergoing hip fracture surgery: a meta-analysis.
Association between dementia and mortality in the elderly patients undergoing hip fracture surgery: a meta-analysis.
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DOI：
10.1186/s13018-018-0988-6
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发表时间：
2018-11-23
影响因子：
2.6
通讯作者：
Liang Y
中科院分区：
文献类型：
--
作者：
Bai J;Zhang P;Liang X;Wu Z;Wang J;Liang Y
本研究旨在验证接受髋部骨折手术的老年人中痴呆与死亡率之间的关联，并评估髋部骨折手术后痴呆患者的死亡率。检索PubMed、Embase和Web of Science，直至2018年4月，无语言限制。两名评价者选择相关研究，评估研究质量，并独立提取数据。在所有分析中，使用随机效应模型推导风险比（RR）和95%置信区间（CI）。终点包括30天、6个月、1年和1年以上死亡率。本次Meta分析遵循PRISMA声明，使用stata14.0软件进行。痴呆显著增加髋部骨折患者术后30天的死亡率[RR = 1.57，95%CI（1.29，1.90），P<0.00]，6个月[RR = 1.97，95%CI（1.47，2.63），P<0.00]、1年[RR = 1.77，95% CI（1.54，2.04），P<0.00]、1年以上随访[RR = 1.60，95% CI（1.30，1.96），P<0.00]。髋部骨折术后30天死亡率[ES = 12%，95%CI（8%，15%）]、6个月死亡率[ES = 32%，95%CI（8%，15%）]（17%，48%）]、1年[ES = 39%，95% CI（35%，43%）]和1年以上随访[ES = 45%，95% CI（32%，58%）]。我们的荟萃分析显示，髋部骨折手术后痴呆患者的死亡率分别为12%、32%、39%和45%，在30天、6个月、1年和1年以上的随访中，髋部骨折手术后痴呆患者的死亡率分别增加了1.57、1.97、1.77和1.60倍。
This study was designed to verify the association between dementia and mortality in the elderly undergoing hip fracture surgery, and assessed the mortality of patients with dementia after hip fracture surgery. PubMed, Embase, and Web of Science were searched until April, 2018 without language restrictions. Two reviewers selected related studies, assessed study quality, and extracted data independently. Risk ratios (RRs) with 95% confidence intervals (CI) were derived using random-effects model throughout all analyses. The endpoints included 30-day, 6-month, 1-year, and more than 1-year mortality. This meta-analysis was performed following PRISMA statement and carried out by using stata14.0 software. Dementia significantly increased postoperative mortality of patients suffered from hip fracture in 30-day [RR = 1.57, 95% CI (1.29, 1.90), P<0.00], 6-month [RR = 1.97, 95% CI (1.47, 2.63), P<0.00], 1-year [RR = 1.77, 95% CI (1.54, 2.04), P<0.00], and more than 1-year follow up [RR = 1.60, 95% CI (1.30, 1.96), P<0.00] respectively. The mortality of dementia patients after hip fracture surgery in 30-day [ES = 12%, 95% CI (8%, 15%)], 6-month [ES = 32%, 95% CI (17%, 48%)], 1-year [ES = 39%, 95% CI (35%, 43%)], and more than 1-year follow up [ES = 45%, 95% CI (32%, 58%)]. Our meta-analysis demonstrated that the mortality of patients with dementia suffered from hip fracture surgery is 12%, 32%, 39%, and 45%, and dementia increased 1.57, 1.97, 1.77, and 1.60-fold mortality in patients undergoing hip fracture surgery in 30-day, 6-month, 1-year, and more than 1-year follow up respectively.
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影响因子：
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作者：
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