Surface alteration of Saccharomyces cerevisiae induced by thymol and eugenol
Surface alteration of Saccharomyces cerevisiae induced by thymol and eugenol
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DOI：
10.1111/j.1472-765x.2004.01511.x
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发表时间：
2004-01-01
影响因子：
2.4
通讯作者：
Remmal, A
中科院分区：
文献类型：
--
作者：
Bennis, S;Chami, F;Remmal, A
目的：本研究的目的是提供一些信息，麝香草酚和丁香酚的杀菌作用的机制，酚类主要成分的百里香和丁香精油分别。酿酒酵母被用作酵母model.Methods和结果：与这些成分的酵母细胞的处理，导致其溶解所示的物质在260 nm处吸收的释放。此外，扫描电子显微镜观察显示，处理过的细胞的表面被显着damage.Conclusions：麝香草酚和丁香酚的抗真菌活性涉及的酵母的细胞膜和细胞壁的改变。意义和影响的研究：这项工作是一个初步的贡献，旨在开发新一代的高效和天然的抗真菌剂。
Aims: This study aims to bring some information about the mechanism of the fungicidal action of thymol and eugenol; phenolic major components of thyme and clove essential oils respectively. Saccharomyces cerevisiae was used as yeast model.Methods and Results: Treatment of yeast cells with these components led to their lysis as shown by the release of substances absorbing at 260 nm. In addition, scanning electron microscope observations revealed that the surface of the treated cells was significantly damaged.Conclusions: Antifungal activity of thymol and eugenol involve alteration of both membrane and cell wall of the yeast.Significance and Impact of the Study: This work is a preliminary contribution aiming to develop a new generation of efficient and natural antifungal agents.