Rapid Handheld Continuous Electroencephalogram (EEG) Has the Potential to Detect Delirium in Older Adults.
Rapid Handheld Continuous Electroencephalogram (EEG) Has the Potential to Detect Delirium in Older Adults.
复制标题
DOI：
10.1097/dcc.0000000000000502
复制
发表时间：
2022-01-01
期刊：
影响因子：
--
通讯作者：
Olson DM
中科院分区：
文献类型：
--
作者：
Mulkey MA;Gantt LT;Hardin SR;Munro CL;Everhart DE;Kim S;Schoeman AM;Roberson DW;McAuliffe M;Olson DM
谵妄相关的生化紊乱导致电变化，可以在脑电图（EEG）模式中检测到，随后是行为体征和症状。使用有限导联EEG的研究表明，在区分谵妄与其他原因时，有谵妄和无谵妄的患者之间存在很大差异。手持式快速EEG设备可能能够在症状发作之前检测到谵妄。因此，提供了一种客观的生理学方法来检测谵妄时，它是最适合干预。探索快速EEG检测与谵妄状态一致的波形模式变化的潜力。这项前瞻性探索性初步研究使用相关设计和混合模型来探索手持式便携式EEG数据与谵妄状态之间的关系。虽然使用谱密度分析来检测EEG衍生比率的统计学差异的机会最小化，但谵妄患者的睡眠/觉醒比率往往较高。有限导联EEG可能有助于预测老年危重患者的不良结局和谵妄风险。虽然这一人群的死亡风险最高，但目前的临床评估不容易识别谵妄。因此，需要进一步研究有限导联EEG用于谵妄检测。
Delirium related biochemical derangements lead to electrical changes that can be detected in electroencephalographic (EEG) patterns followed by behavioral signs and symptoms. Studies using limited lead EEG show a large difference between patients with and without delirium while discriminating delirium from other causes. Hand-held rapid EEG devices may be capable of detecting delirium prior to symptom onset. Thus, providing an objective physiological method to detect delirium when it is most amenable to interventions. To explore the potential for rapid EEG to detect waveform pattern changes consistent with delirium status. This prospective exploratory pilot study used a correlational design and mixed models to explore the relationships between hand-held portable EEG data and delirium status While being under powered minimized opportunities to detect statistical differences in EEG derived ratios using spectral density analysis, sleep/wake ratios tended to be higher in patients with delirium. Limited lead EEG may be useful in predicting adverse outcomes and risk for delirium in older critically ill patients. Although this population is at highest risk for mortality, delirium is not easily identified by current clinical assessments. Therefore, further investigation of limited lead EEG for delirium detection is warranted.