Chaotic tip trajectories of a single spiral wave in the presence of heterogeneities.
Chaotic tip trajectories of a single spiral wave in the presence of heterogeneities.
复制标题
存在异质性时单个螺旋波的混沌尖端轨迹。
DOI：
10.1103/physreve.99.062409
复制
发表时间：
2019
期刊：
影响因子：
--
通讯作者：
Rappel,Wouter-Jan
中科院分区：
文献类型：
--
作者：
Lombardo,DanielM;Rappel,Wouter-Jan
螺旋波已经在各种物理、化学和生物系统中被观察到。它们在心律失常（包括纤颤）中起主要作用，其中观察到的不规则激活模式通常被认为是由多个不稳定螺旋波的连续破裂引起的。通过对不同心脏组织电生理模型的空间扩展模拟，我们发现在存在异质性的情况下，单个螺旋波可以显示混沌的尖端轨迹，与纤颤一致。我们还表明，模拟的螺旋尖端动力学，包括混沌轨迹，可以通过一个简单的粒子模型来捕获，该模型只描述螺旋尖端的动力学。这表明，螺旋波的破裂或与其他波的相互作用并不是引发螺旋波混沌的必要条件。
Spiral waves have been observed in a variety of physical, chemical, and biological systems. They play a major role in cardiac arrhythmias, including fibrillation, where the observed irregular activation patterns are generally thought to arise from the continuous breakup of multiple unstable spiral waves. Using spatially extended simulations of different electrophysiological models of cardiac tissue, we show that a single spiral wave in the presence of heterogeneities can display chaotic tip trajectories, consistent with fibrillation. We also show that the simulated spiral tip dynamics, including chaotic trajectories, can be captured by a simple particle model which only describes the dynamics of the spiral tip. This shows that spiral wave breakup, or interactions with other waves, are not necessary to initiate chaos in spiral waves.