Meeting report: NCI think tanks in cancer biology.
Meeting report: NCI think tanks in cancer biology.
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会议报告：NCI 癌症生物学智库。
DOI：
10.1158/0008-5472.can-05-1817
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发表时间：
2005
期刊：
影响因子：
11.2
通讯作者：
D. Singer
中科院分区：
文献类型：
--
作者：
J. Sogn;H. Anton;D. Singer
在过去的一年半里，NCI癌症生物学部门一直在评估癌症生物学的状况，目标是为不久的将来制定一个研究议程，以加速癌症研究的进展。我们的目标是确定新出现的概念和有希望的机会，在九个科学领域的调查与不寻常的承诺，迅速取得进展。召开了一系列称为“智囊团”的会议，每次会议由15至25名专家组成。总共有160多位癌症研究和相关领域的领导者讨论了各自学科的科学现状，预测了其发展轨迹，并建议NCI可以或应该做些什么来促进进展。除了强调必须继续支持秘书处发起的研究之外，智囊团还确定了一些首要主题。其中至关重要的是需要支持综合癌症生物学的发展，并通过建立互动研究的基础设施来鼓励对肿瘤微环境的研究。还就正常和肿瘤状态的比较研究的重要性以及支持协作、跨学科研究和培训的机制的发展达成了共识。
Over the past year and a half, the Division of Cancer Biology of NCI has been assessing the state of cancer biology, with the goal of developing a research agenda for the near future that would accelerate progress in cancer research. Our goal was to identify emerging concepts and promising opportunities for investigation across nine scientific areas with unusual promise for rapid progress. A series of meetings called Think Tanks was convened, each involving a panel of 15-25 experts. In all, over 160 leaders in cancer research and related fields discussed the current state of science in their disciplines, projected its trajectory and recommended what NCI could or should do to facilitate progress. In addition to emphasizing the importance of continued support for investigator-initiated research, the Think Tanks permitted identification of a number of overarching themes. Critical among them was the need to support the development of integrative cancer biology and to encourage studies of the tumor microenvironment by establishing an infrastructure for interactive research. There was also consensus about the importance of comparative studies of normal and tumor states, and development of mechanisms for supporting collaborative, interdisciplinary research and training.