Synthesis and reaction of the first oxazol-4-ylboronates: Useful reagents for the preparation of the oxazole-containing biaryl compounds
Synthesis and reaction of the first oxazol-4-ylboronates: Useful reagents for the preparation of the oxazole-containing biaryl compounds
复制标题
DOI：
10.1055/s-2006-932471
复制
发表时间：
2006-03-02
期刊：
影响因子：
2
通讯作者：
Inoue, M
中科院分区：
文献类型：
--
作者：
Araki, H;Katoh, T;Inoue, M
由相应的4-溴和4-三氟甲磺酰氧基恶唑制备了第一批恶唑-4-基硼酸盐。铃木偶联使用所得到的硼试剂与各种芳基卤化物。包括苯环、吡啶环、恶唑环和噻唑环，在钯催化剂的存在下，以中高收率制备了含恶唑的联芳基化合物。
The first oxazol-4-ylboronates were prepared from the corresponding 4-bromo- and 4-trifluoromethanesulfonyloxy-oxazoles. The Suzuki coupling using the resulting boron reagents with various aryl halides. including benzene, pyridine, oxazole and thiazole rings, in the presence of palladium catalyst proceeded to produce the oxazole-containing biaryl compounds in moderate to good yields.