EFFECTS ON THE CHILD OF ALCOHOL ABUSE DURING PREGNANCY: Retrospective and Prospective Studies
EFFECTS ON THE CHILD OF ALCOHOL ABUSE DURING PREGNANCY: Retrospective and Prospective Studies
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怀孕期间酗酒对孩子的影响：回顾性和前瞻性研究
DOI：
10.1111/j.1651-2227.1979.tb06170.x
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发表时间：
1979
期刊：
影响因子：
--
通讯作者：
A. Hrbek
中科院分区：
文献类型：
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作者：
R. Olegård;K. Sabel;M. Aronsson;B. Sandín;P. R. Johansson;C. Carlsson;M. Kyllerman;K. Iversen;A. Hrbek
抽象的。奥列加德，R.，萨贝尔，K.-G.，Aronsson，M.，Sandin，B.，Johansson，P.R.Carlsson，C.，Kyllerman，M.，Iversen，K.和Hrbek，A.(瑞典哥德堡利尔赫根医院儿科，东部医院，哥德堡大学第二精神病诊所和诺德姆酒精诊所)。孕期酗酒对孩子的影响。回顾研究和前瞻性研究。对酗酒妇女的儿童进行的回顾和前瞻性调查表明，每300例分娩中就有一例胎儿酒精损伤，其中一半患有完全性胎儿酒精综合征。围产期和婴儿死亡率增加了七到十倍，低出生体重(<；2500克)，早产(<；37周)和小于胎龄(<；-2S.D.)。分别增加了8倍、3倍和12倍。出生时体型较小与晚年智力下降有关，58%的人智商低于85，19%的人智商低于70。8%的人有脑性瘫痪。与母亲醉酒有关的脑瘫发病率为1/5000分娩，即每6例脑瘫病例。在妊娠早期可以诱导清醒，但不能通过神经表现和诱发反应脑电测定来保护功能性脑功能障碍的情况下，对怀孕和治疗期间的酒精中毒妇女的追踪对宫内发育有有利的效果。酒精对胎儿的损害是目前已知的最大的健康危害，它是一种可以预防的有毒物质。
Abstract. Olegård, R., Sabel, K.‐G., Aronsson, M., Sandin, B., Johansson, P. R. Carlsson, C., Kyllerman, M., Iversen, K. and Hrbek, A. (Departments of Paediatrics, East Hospital, University of Göteborg and Psychiatric Clinic II and Nordhem Alcoholic Clinic, Lillhagen Hospital, Göteborg, Sweden). Effect on the child of alcohol abuse during pregnancy. Retrospective and prospective studies. Retrospective and prospective investigations of children to alcoholic women gave an incidence of fetal alcohol lesion of one per 300 deliveries of whom half had the complete fetal alcohol syndrome. Perinatal and infant mortalities were increased seven to tenfold and low birth weight (<2500 g), preterm deliveries (<37 weeks) and smallness for gestational age (<‐2 S.D.) were increased eightfold, threefold and twelvefold, respectively. Small size at birth correlated with reduced mental performance later in life, 58% had IQ below 85 and 19% below 70. 8% had cerebral palsy. The incidence of cerebral palsy associated with maternal inebriety was 1/5000 deliveries, i.e. every sixth case of cerebral palsy. Tracing of alcoholic women during pregnancy and treatment gave favourable effect on intrauterine growth when sobriety could be induced early in pregnancy but could not protect from functional brain disturbance measured by neurological performance and by evoked response electroencephalography. Damage to the fetus by alcohol is now the largest known health hazard by a noxious agent that is preventable.