Laser Doppler vibrometry of the middle ear in humans: derivation dependence, variability, and bilateral differences
Laser Doppler vibrometry of the middle ear in humans: derivation dependence, variability, and bilateral differences
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DOI：
10.3390/medicina45110113
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发表时间：
2009-01-01
影响因子：
2.6
通讯作者：
Zahnert, Thomas
中科院分区：
文献类型：
--
作者：
Arechvo, Irina;Lasurashvili, Nikoloz;Zahnert, Thomas
目标。利用激光多普勒振动仪（LDV）研究了耳膜振动特性的衍生依赖性、个体间和个体内/个体间变异性、双侧差异。材料和方法。对31名听力正常的成年人进行了检查。在每个受试者中，双耳连续受到覆盖500-3700 hz频率的啁啾声刺激。将激光束射入鼓膜表面，连续地从鼓膜表面拾取反射。不同耳膜位置的LDV曲线具有不同的特征。对于1500 Hz以上的刺激频率成分，推导区依赖性尤为明显。受试者间LDV参数变异性大于受试者内/兴趣参数变异性。在2000赫兹以上的频率上，主体间的差异看起来是有选择性的。在重复记录下，LDV参数保持稳定。兴趣差异，如果出现的话，主要是关于不同频段的大小。经验丰富的研究者和初学研究者所记录的LDV波形是相似的。双侧导出的LDV曲线有规律地彼此不同。在个别情况下，双边偏差近似于主体间偏差。在估计实际LDV记录时，应考虑到吃鼓上的推导区域。在不同个体的重复记录中，LDV波形是稳定的，而研究者的经验对LDV的主要特征只有轻微的影响。由于双侧中耳传递功能的差异，在疑似病理耳的LDV检测中，很难以对侧健康耳的LDV记录作为合适的参考样本。
Objective. Derivation dependence, inter- and intrasubject/intertest variability, bilateral differences of the eardrum vibration characteristics have been investigated using laser Doppler vibrometry (LDV).Material and methods. A total of 31 normally hearing adults were examined. In each subject, both ears were consecutively stimulated by the chirp acoustic stimulus that covered 500-3700-Hz frequencies. The laser beam was directed to and the reflection was consecutively picked up from the tympanic membrane surface.Results. LDV curves derived from different eardrum loci possessed dissimilar characteristics. The derivation area dependence was particularly apparent for the stimulus frequency constituents above 1500 Hz. The intersubject variability of LDV parameters exceeded the intrasubject/intertest one. The intersubject divergences looked selectively distinct for the frequencies over 2000 Hz. Under repeated recordings, LDV parameters remained stable. The intertest differences, if appeared, concerned predominantly the magnitudes of separate frequency bands. LDV waveforms registered by experienced and beginner investigators were alike. Bilaterally derived LDV curves regularly differed from each other. In individual cases, the bilateral divergences approximated the intersubject deviation.Conclusions. The derivation area on the eat-drum should be taken into account when estimating the actual LDV recording. Over repeated recordings in separate individuals, LDV waveforms are stable while the experience of investigator has slight if any influence on the principal LDV characteristics. Due to bilateral differences in the middle ear transfer function, in LDV testing of the ear suspected to the pathology, LDV recording from the opposite healthy ear could hardly be taken as an appropriate reference sample.