Update on Surgical Management of Renal Cell Carcinoma with Venous Extension

Update on Surgical Management of Renal Cell Carcinoma with Venous Extension
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DOI:
10.1007/s11934-011-0222-0
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发表时间:
2012-02-01
影响因子:
2.6
通讯作者:
Gonzalez, Javier
Gonzalez, Javier
中科院分区:
医学3区
文献类型:
--
作者:
Gonzalez, Javier

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肾细胞癌的静脉内转移是泌尿外科肿瘤学中最激烈的争论话题之一。在缺乏有效的替代治疗方法的情况下,完全手术切除原发肿瘤及其沿腔静脉的延伸沿着是治愈的唯一希望。因此,积极的治疗方法已被确立为治疗的主要方法。血管内肿瘤侵袭的生物学的理解和相当大的进展,在诊断和治疗领域的这一实体,创新的手术和系统的策略,最近的进展,已经完全重新定义了这些患者的管理。进行PubMed-MEDLINE检索,以识别关于肾细胞癌伴静脉内肿瘤扩展的术前评估和手术管理的相关文章,以提供关于这一始终具有挑战性的主题的最新知识。
Intravenous extension of renal cell carcinoma remains one of the most intense debate topics in urologic oncology. In the absence of effective alternative treatment, complete surgical removal of the primary tumor with its extension along the vena cava is the only hope for a potential cure. For this reason, an aggressive approach has been established as the mainstay of treatment. Recent advances in the understanding of the biology of intravascular tumor invasion and the considerable progress in the fields of diagnosis and treatment of this entity, with innovative surgical and systemic strategies, have completely redefined the management of these patients. A PubMed-MEDLINE search was conducted to identify relevant articles on the preoperative assessment and surgical management of renal cell carcinoma with intravenous tumor extension to provide updated knowledge on this always challenging topic.