A subinhibitory concentration of clarithromycin inhibits Mycobactetium avium biofilm formation
A subinhibitory concentration of clarithromycin inhibits Mycobactetium avium biofilm formation
复制标题
DOI：
10.1128/aac.48.12.4907-4910.2004
复制
发表时间：
2004-12-01
影响因子：
4.9
通讯作者：
Bermudez, LE
中科院分区：
文献类型：
--
作者：
Carter, G;Young, LS;Bermudez, LE
鸟分枝杆菌引起免疫抑制个体的播散性感染和慢性肺病患者的肺部感染。M.鸟类在环境中并可能在人的呼吸道中形成生物膜。具有抗菌活性的抗生素可抑制生物膜的形成。克拉霉素抑制生物膜形成，但对已形成的生物膜无活性。
Mycobacterium avium causes disseminated infection in immunosuppressed individuals and lung infection in patients with chronic lung diseases. M. avium forms biofilm in the environment and possibly in human airways. Antibiotics with activity against the bacterium could inhibit biofilm formation. Clarithromycin inhibits biofilm formation but has no activity against established biofilm.