Inflammation in diabetic kidney disease
Inflammation in diabetic kidney disease
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DOI：
10.4239/wjd.v5.i4.431
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发表时间：
2014-08-15
影响因子：
4.2
通讯作者：
Navarro-Gonzalez, Juan F.
中科院分区：
文献类型：
--
作者：
Garcia-Garcia, Patricia M.;Getino-Melian, Maria A.;Navarro-Gonzalez, Juan F.
糖尿病在世界范围内引起严重的健康问题。糖尿病的发病机制是多因素的，由遗传和环境因素的相互作用引起，这些因素触发了复杂的病理生理事件网络，并伴有代谢和血流动力学改变。在这种情况下，炎症已成为一个关键的病理生理机制。新的致病途径将为预防或未来的治疗提供目标。本文就炎症在糖尿病中的作用，特别是炎症细胞因子的研究进展作一综述。(C)2014百世登出版集团股份有限公司All rights reserved.
Diabetes mellitus entails significant health problems worldwide. The pathogenesis of diabetes is multifactorial, resulting from interactions of both genetic and environmental factors that trigger a complex network of pathophysiological events, with metabolic and hemodynamic alterations. In this context, inflammation has emerged as a key pathophysiology mechanism. New pathogenic pathways will provide targets for prevention or future treatments. This review will focus on the implications of inflammation in diabetes mellitus, with special attention to inflammatory cytokines. (C) 2014 Baishideng Publishing Group Inc. All rights reserved.