Comparison of extrapyramidal signs in dementia with Lewy bodies and Parkinson's disease

Comparison of extrapyramidal signs in dementia with Lewy bodies and Parkinson's disease
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DOI:
10.1176/appi.neuropsych.13.3.374
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发表时间:
2001-06-01
影响因子:
2.9
通讯作者:
Larsen, JP
Larsen, JP
中科院分区:
医学4区
文献类型:
--
作者:
Aarsland, D;Ballard, C;Larsen, JP

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比较98例路易体痴呆(DLB)和130例药物敏感性帕金森病(PD)患者的锥体外系体征(EPS)。DLB患者在评估时和疾病发作时年龄较大,认知受损程度更高,并且疾病持续时间比PD患者短。67例DLB患者(68%)显示EPS。58例有完整数据的DLB患者比PD患者有更严重的动作震颤、身体运动迟缓、从椅子上出现困难以及面部表情、步态和僵硬症状(均P
Extrapyramidal signs (EPS) were compared in 98 dementia with Lewy bodies (DLB) and 130 medication-responsive Parkinson's disease (PD) patients. DLB patients were older at assessment and at disease onset, were cognitively more impaired, and had a shorter duration of disease than PD patients. Sixty-seven DLB patients (68%) showed EPS. The 58 DLB patients with complete data had more severe action tremor, body bradykinesia, difficulty arising from a chair, and facial expression, gait, and rigidity symptoms than PD patients (all P