Multimorbidity is associated with anxiety in older adults in the Health and Retirement Study.
Multimorbidity is associated with anxiety in older adults in the Health and Retirement Study.
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DOI：
10.1002/gps.4532
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发表时间：
2016-10
影响因子：
4
通讯作者：
Beaudreau SA
中科院分区：
文献类型：
--
作者：
Gould CE;O'Hara R;Goldstein MK;Beaudreau SA
本研究确定了美国老年人的全国代表性样本中，医疗状况的数量是否与焦虑发生率增加有关，以及三联症是否与焦虑有关。我们确定与抑郁症状相比，多发病的结果是否是焦虑所独有的。 2006 年健康与退休研究浪潮中，4,219 名参与者（65 岁或以上）完成了焦虑和抑郁测量。逻辑回归模型的结果是焦虑升高（5 项贝克焦虑量表≥12）或抑郁症状（8 项流行病学研究中心抑郁量表≥12）。预测变量是对医生诊断的 7 种疾病的自我报告的统计：关节炎、癌症、糖尿病、心脏病、高血压、肺病和中风。根据年龄、性别以及抑郁或焦虑症状对分析进行了调整。使用 Bonferroni 校正卡方分析检查焦虑或抑郁症状加剧与 35 个三联体医疗状况之间的关联。三种或三种以上的医疗状况使焦虑程度增加 2.30 倍（95% CI：1.44-4.01）。 20 个三联征与焦虑加剧相关，而 13 个三联征与抑郁症状相关。大多数三联征中存在七种疾病中的六种（中风除外）。一些医疗状况和特定状况与焦虑的发生率增加有关。与抑郁症状升高相比，焦虑与更高的多重发病率相关。由于焦虑和抑郁会导致显着的发病率，因此在评估患有多种疾病的老年人时考虑这些心理健康症状可能是有益的。
The present study determined whether the number of medical conditions was associated with increased occurrence of anxiety and whether triads of medical conditions were associated with anxiety in a nationally representative sample of older Americans. We determined whether multimorbidity findings were unique to anxiety as compared with depressive symptoms. 4,219 participants (65 or older) completed anxiety and depression measures in the Health and Retirement Study 2006 wave. The logistic regression models’ outcome was elevated anxiety (≥12 on 5-item Beck Anxiety Inventory) or depressive symptoms (≥ on 8-item Center for Epidemiological Studies Depression Scale). The predictor variable was a tally of 7 self-report of doctor-diagnosed conditions: arthritis, cancer, diabetes, heart conditions, high blood pressure, lung disease, and stroke. Analyses were adjusted for age, gender, and depressive or anxiety symptoms. Associations among elevated anxiety or depressive symptoms and 35 triads of medical conditions were examined using Bonferroni corrected chi-square analyses. Three or more medical conditions conferred a 2.30-fold increase in elevated anxiety (95% CI: 1.44-4.01). Twenty triads were associated with elevated anxiety as compared with 13 associated with depressive symptoms. Six of 7 medical conditions, with the exception being stroke, were present in the majority of triads. Number of medical conditions and specific conditions are associated with increased occurrence of elevated anxiety. Compared with elevated depressive symptoms, anxiety is associated with greater multimorbidity. Since anxiety and depression cause significant morbidity, it may be beneficial to consider these mental health symptoms when evaluating older adults with multimorbidity.