Multicystic mesothelioma of the pericardium
Multicystic mesothelioma of the pericardium
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心包多囊性间皮瘤
DOI：
10.1111/j.1440-1827.2011.02654.x
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发表时间：
2011
期刊：
影响因子：
--
通讯作者：
Fukayama M.
中科院分区：
文献类型：
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作者：
Morita S;Goto A;Sakatani T;Ota S;Murakawa T;Nakajima J;Maeda E;Fukayama M.
多囊性间皮瘤是一种公认但罕见的浆液性肿瘤，主要发生于女性腹膜，被认为是一种良性病变。这是第二例心包多囊间皮瘤的报告，它采取了致命的临床过程。患者男，63岁，表现为凹陷性水肿、呼吸急促和声音嘶哑。放射学检查发现心包囊实性肿瘤，肿瘤不断向纵隔和肝脏延伸。心包活检见单层间皮细胞排列的微囊性肿瘤，无异型性，诊断为多囊性间皮瘤。无法进行根治性手术，三年零四个月后，患者因肿瘤直接压迫心脏而死亡。尸检发现，肿瘤除了纵隔和肝脏外，还直接延伸到右胸腔和右肺。未发现恶性转化或转移瘤。
Multicystic mesothelioma is a well recognized but rare serosal tumor which mainly arises from the peritoneum in women and is considered as a benign lesion. This is the second case report of pericardial multicystic mesothelioma, which took a fatal clinical course. A 63‐year‐old man presented with pitting edema, shortness of breath, and hoarseness. Radiological investigations revealed solid and cystic tumor of the pericardium which was continuously extending into the mediastinum and the liver. Pericardial biopsy showed micro‐cystic tumor lined by single layer of mesothelial cells without atypia, and the diagnosis was multicystic mesothelioma. Curative surgery could not be performed, and three years and four months later, the patient died because of the direct compression of the heart by the tumor. At autopsy, the tumor was found to be directly extending into the right pleural cavity and the right lung, besides the mediastinum and the liver. Neither malignant transformation nor metastatic tumor was identified.