Development of novel biodegradable Au nanocomposite hydrogels based on wheat: For inactivation of bacteria
Development of novel biodegradable Au nanocomposite hydrogels based on wheat: For inactivation of bacteria
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DOI：
10.1016/j.carbpol.2012.12.006
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发表时间：
2013-02-15
影响因子：
11.2
通讯作者：
Raju, Konduru Mohana
中科院分区：
文献类型：
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作者：
Jayaramudu, Tippabattini;Raghavendra, Gownolla Malegowd;Raju, Konduru Mohana
设计并制备了新型可生物降解的金纳米复合水凝胶作为抗菌剂。以丙烯酰胺（AM）和小麦分离蛋白（WPI）为原料，制备了可生物降解的金纳米复合水凝胶。通过用印楝（印楝叶）的叶提取物还原HAuCl 4中心点XH 2 O，形成水凝胶网络，将金纳米颗粒制备为金胶体。采用傅立叶变换红外光谱（FTIR）、紫外-可见光谱（UV-vis）、X射线衍射（XRD）、热重分析（TGA）、差示扫描量热法（DSC）、扫描电子显微镜-能量色散谱（SEM-EDS）和透射电子显微镜（TEM）对所制备的生物可降解水凝胶进行了表征。测试了所开发的可生物降解的金纳米颗粒复合水凝胶的抗菌性能。结果表明，这些可生物降解的金纳米复合水凝胶可用作抗菌应用的潜在候选者。(C)2012爱思唯尔有限公司保留所有权利。
The design and fabrication of novel biodegradable gold nanocomposites hydrogels were developed as antibacterial agent. Biodegradable gold nanocomposite hydrogels were developed by using acrylamide (AM) and wheat protein isolate (WPI). The gold nanoparticles were prepared as a gold colloid by reducing HAuCl4 center dot XH2O with leaf extracts of Azadirachta indica (neem leaf) that formed hydrogel network. The characterization of developed biodegradable hydrogels were studied using fourier transforms infrared (FTIR) spectroscopy, ultraviolet-visible (UV-vis) spectroscopy, X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), differential scanning calorimetry (DSC), scanning electron microscopy-energy dispersive spectroscopy (SEM-EDS) and transmission electron microscopy (TEM). The biodegradable gold nanoparticle composite hydrogels developed were tested for antibacterial properties. The results indicate that these biodegradable gold nanocomposite hydrogels can be used as potential candidates for antibacterial applications. (C) 2012 Elsevier Ltd. All rights reserved.