Navajo jaundice: a variant of neonatal hyperbilirubinemia associated with breast feeding.

Navajo jaundice: a variant of neonatal hyperbilirubinemia associated with breast feeding.
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纳瓦霍黄疸:与母乳喂养相关的新生儿高胆红素血症的一种变体。

DOI:
10.1016/s0022-3476(74)80410-5
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发表时间:
1974
期刊:
The Journal of pediatrics
影响因子:
--
通讯作者:
Michael I. Cohen
Michael I. Cohen
中科院分区:
--
文献类型:
--
作者:
Joel Saland;Joel Saland;Helen McNamara;Helen McNamara;Michael I. Cohen;Michael I. Cohen

文献摘要

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A clinical and chemical appraisal of 47 newborn Navajo infants demonstrated a high incidence of unconjugated hyperbilirubinemia during the first week of life. Within this study population two subgroups were identified: (1) breast-fed infants in whom inhibition of bilirubin glucuronyl transferase activity was related to a substance in colostrum and breast milk in the first days of life and (2) a smaller subgroup of bottle-fed infants who had significant jaundice when compared with a control population from New York. The serum bilirubin concentrations of the Navajo bottle-fed infants never achieved those of the breast-fed subgroup. These data suggest that to some extent the neonatal unconjugated hyperbilirubinemia noted in the Navajo Indian is related to breast feeding, with earlier transmission of the presumed inhibitor substance than previously observed in a Caucasian population.