Positron emission tomography/computerized tomography for tumor response assessment-a review of clinical practices and radiomics studies.
Positron emission tomography/computerized tomography for tumor response assessment-a review of clinical practices and radiomics studies.
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DOI：
10.21037/tcr.2016.07.12
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发表时间：
2016-08
影响因子：
0.9
通讯作者：
Chen W
中科院分区：
文献类型：
--
作者：
Lu W;Chen W
即使最近在癌症诊断和治疗方面取得了进展，许多癌症的治疗结果仍然令人沮丧。患者对相同的治疗方案往往表现出不同的反应，支持个性化医疗的发展。18F-FDG PET/CT已常规用于评估肿瘤缓解、预测结局和指导个性化治疗。这些评估主要基于医生的主观或半定量评估。放射组学的最新发展为肿瘤反应评估提供了一种有前途的客观方法，其使用计算机化工具来提取大量图像特征，这些图像特征捕获了目前临床上未使用的具有预后价值的额外信息。本文就PET/CT及其放射组学在肿瘤缓解评估中的应用进行综述。最后，我们讨论了一些挑战和未来前景。
Even with recent advances in cancer diagnosis and therapy, treatment outcomes for many cancers remain dismal. Patients often show different response to the same therapy regimen, supporting the development of personalized medicine. 18F-FDG PET/CT has been used routinely in the assessment of tumor response, in prediction of outcomes, and in guiding personalized treatment. These assessments are mainly based on physician’s subjective or semi-quantitative evaluation. Recent development in Radiomics provides a promising objective way for tumor response assessment, which uses computerized tools to extract a large number of image features that capture additional information not currently used in clinic that has prognostic value. In this review, we summarized the clinical use of PET/CT and the PET/CT Radiomics studies for tumor response assessment. Finally, we discussed some challenges and future perspectives.
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影响因子：
120.7
作者：
Chun, Yun Shin;Vauthey, Jean-Nicolas;Boonsirikamchai, Piyaporn;Maru, Dipen M.;Kopetz, Scott;Palavecino, Martin;Curley, Steven A.;Abdalla, Eddie K.;Kaur, Harmeet;Charnsangavej, Chusilp;Loyer, Evelyne M.
通讯作者：
Loyer, Evelyne M.
DOI：
10.1158/1078-0432.ccr-14-0990
发表时间：
2015-01-15
期刊：
Clinical cancer research : an official journal of the American Association for Cancer Research
影响因子：
--
作者：
O'Connor JP;Rose CJ;Waterton JC;Carano RA;Parker GJ;Jackson A
通讯作者：
Jackson A
影响因子：
3.8
作者：
Belhassen, Saoussen;Zaidi, Habib
通讯作者：
Zaidi, Habib
影响因子：
45.3
作者：
Moeller, Benjamin J.;Rana, Vishal;Schwartz, David L.
通讯作者：
Schwartz, David L.
影响因子：
9.3
作者：
Hatt, Mathieu;Rest, Catherine Cheze-Le;Visvikis, Dimitris
通讯作者：
Visvikis, Dimitris