ISOLATION OF FRACTIONS RICH IN HUMAN Y SPERM
ISOLATION OF FRACTIONS RICH IN HUMAN Y SPERM
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DOI：
10.1038/246421a0
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发表时间：
1973-01-01
期刊：
影响因子：
64.8
通讯作者：
NISHINO, M
中科院分区：
文献类型：
--
作者：
ERICSSON, RJ;LANGEVIN, CN;NISHINO, M
分离人类X和Y精子的研究现在是可行的，这是因为Y染色体1，2染有荧光染料。在其他哺乳动物的精子中仍然不可能识别Y染色体，可能除了大猩猩精子3，但当人类精子被这种荧光色素染色并在荧光显微镜下观察时，大约一半的精子显示出Y小体。Y小体是Y染色体长臂的末端，显示为一个明亮的荧光点4。识别Y染色体的能力使收集关于X和Y精子的数据成为可能。
RESEARCH into the isolation of human X and Y sperm is now feasible because of the fluorochrome quinacrine that stains the Y chromosome1,2. It is still impossible to identify the Y chromosome in sperm of other mammals, with the possible exception of gorilla sperm3, but when human sperm are stained with this fluorochrome and viewed under fluorescence microscopy, approximately half of them reveal a Y body. The Y body is the distal end of the long arm of the Y chromosome and shows up as a bright fluorescent dot4. The ability to identify the Y chromosome makes possible the collection of data on X and Y sperm5,6.