Spirocurvulaide, a novel spirobicyclic polyketide from a marine fungus Curvularia sp. IFB-Z10
Spirocurvulaide, a novel spirobicyclic polyketide from a marine fungus Curvularia sp. IFB-Z10
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Spirocurvulaide 是一种来自海洋真菌 Curvularia sp 的新型螺双环聚酮化合物。
DOI：
10.1016/j.phytol.2018.07.011
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发表时间：
2019-02-01
影响因子：
1.7
通讯作者：
Lu, Yan-Hua
中科院分区：
文献类型：
--
作者：
An, Fa-Liang;Liu, Wei-He;Lu, Yan-Hua
螺旋弯孢菌素（Spirocurvulaide，1）是由弯孢菌（Curvularia sp.）IFB-Z 10在水稻固体培养基中产生的一种新型双环聚酮化合物。根据核磁共振（NMR）数据、13 C NMR化学位移的量子化学预测（QCP）和含时密度泛函理论（TDDFT）/ECD计算，确定了其平面结构和绝对构型.对化合物1的生物合成途径进行了讨论。
Spirocurvulaide (1), a novel bicyclic polyketide with an unprecedented spiro[furan-2,2'-naphthalene] ring system, was produced by the fungus Curvularia sp. IFB-Z10 in a solid rice medium. Its planar structure and absolute configuration were established based on nuclear magnetic resonance (NMR) data, quantum chemical predictions (QCP) of C-13 NMR chemical shifts and time-dependent density functional theory (TDDFT)/ECD calculations. A plausible biosynthetic pathway of compound 1 was also discussed.