Proteoglycans and Glycosaminoglycans Improve Toughness of Biocompatible Double Network Hydrogels
Proteoglycans and Glycosaminoglycans Improve Toughness of Biocompatible Double Network Hydrogels
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DOI:
10.1002/adma.201303387
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发表时间:
2014
影响因子:
29.4
通讯作者:
Yu Zhao;Tasuku Nakajima;Jing Jing Yang-Jing;T. Kurokawa;J. Liu;Jishun Lu;Shuji Mizumoto;K. Sugahara-
中科院分区:
文献类型:
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作者:
Yu Zhao;Tasuku Nakajima;Jing Jing Yang-Jing;T. Kurokawa;J. Liu;Jishun Lu;Shuji Mizumoto;K. Sugahara-
Based on the molecular stent concept, a series of tough double-network hydrogels (St-DN gels) made from the components of proteoglycan aggregates - chondroitin sulfate proteoglycans (1), chondroitin sulfate (2), and sodium hyaluronate (3) - are successfully developed in combination with a neutral biocompatible polymer. This work demonstrates a promising method to create biopolymer-based tough hydrogels for biomedical applications.