Recovery of lower cranial nerve function after surgery for medullary brainstem tumors
Recovery of lower cranial nerve function after surgery for medullary brainstem tumors
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DOI：
10.1227/01.neu.0000144782.39430.12
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发表时间：
2005-01-01
期刊：
影响因子：
4.8
通讯作者：
Epstein, F
中科院分区：
文献类型：
--
作者：
Jallo, GI;Shiminski-Maher, T;Epstein, F
目的：尽管对延髓内局灶性肿瘤的最佳治疗仍存在争议，但许多外科医生主张对这些肿瘤患者进行根治性手术。术后并发症可能包括下颅神经功能丧失和严重的运动障碍。根治性手术后下颅神经功能障碍的恢复还没有reportedprevious.METHODS：41名儿童和青少年的肿瘤，涉及髓质进行了1986年和1997年之间的操作。这些患者中有19例（46%）发生了下颅神经功能丧失，需要气管造口术、呼吸机支持和进食胃造口术。一项回顾性分析，这一患者群体和颅神经恢复的时间进行了carried.Results：13（68%）的19例患者的下颅神经功能丧失了充分恢复下颅神经功能。2例患者（111%）有显着改善，他们的下颅神经功能，和4例（21%）仍然没有下颅神经functions.CONCLUSION：下颅功能障碍是常见的手术后内源性延髓肿瘤。然而，大多数需要气管造口术或胃造口术管的患者将恢复脑神经功能。
OBJECTIVE: Although optimal treatment for intrinsic focal tumors of the medulla remains controversial, many surgeons advocate radical surgery for patients with these tumors. Postoperative surgical morbidity may include loss of lower cranial nerve function and significant motor deficits. Recovery of lower cranial nerve dysfunction after radical surgery has not been reported previously.METHODS: Forty-one children and adolescents with tumors involving the medulla underwent operations between 1986 and 1997. Nineteen (46%) of these patients experienced loss of lower cranial nerve function requiring tracheostomy, ventilator support, and feeding gastrostomy. A retrospective analysis of this patient population and the time to cranial nerve recovery was undertaken.RESULTS: Thirteen (68%) of the 19 patients with loss of lower cranial nerve function had full recovery of lower cranial nerve function. Two patients (111%) have had significant improvement in their lower cranial nerve function, and four patients (21%) have remained without lower cranial nerve function.CONCLUSION: Lower cranial dysfunction is common after surgery for intrinsic medullary tumors. However, the majority of patients who require tracheostomy or gastrostomy tubes will recover cranial nerve function.