Reconstruction of individual thyroid doses to the Ukrainian subjects enrolled in the Chernobyl Tissue Bank
Reconstruction of individual thyroid doses to the Ukrainian subjects enrolled in the Chernobyl Tissue Bank
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DOI：
10.1093/rpd/nct096
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发表时间：
2013-10-01
影响因子：
1
通讯作者：
Bouville, A.
中科院分区：
文献类型：
--
作者：
Likhtarov, I.;Thomas, G.;Bouville, A.
切尔诺贝利组织银行(CTB)是一个收集和存储肿瘤甲状腺组织样本的组织，这些样本来自乌克兰和俄罗斯的受试者，这些受试者曾因甲状腺癌接受手术治疗，并因切尔诺贝利事故而暴露于I-131。截至2012年，CTB已经收集了2267名乌克兰居民的甲状腺组织样本，用于辐射研究。除了24名受试者外，所有受试者的算术平均甲状腺剂量和不确定性都已被估计，这些受试者在暴露时没有发现居住地。根据每个受试者可获得的与剂量学相关的信息类型，受试者被分为六组或亚组。剔除可忽略辐射照射的325名受试者，所有受试者甲状腺剂量的算术平均值估计为0.4GY，个体值范围为1mGy至13Gy.个人甲状腺剂量估计的不确定度，以其概率分布的几何标准偏差为特征，范围从1.3到8.7，算术平均值为3.2。
The Chernobyl Tissue Bank (CTB) is an organisation that collects and stores samples of tumoral thyroid tissue obtained from Ukrainian and Russian subjects who were treated surgically for a thyroid cancer and had been exposed to I-131 from the Chernobyl accident. By 2012, the CTB had collected specimens of thyroid tissue from 2267 residents of Ukraine for the purpose of radiation research. Arithmetic mean thyroid doses and uncertainties have been estimated for all but 24 subjects for whom residence at the time of exposure was not found. The subjects have been classified into six groups or sub-groups according to the type of dosimetry-related information that is available for each of them. Excluding the 325 subjects with negligible radiation exposure, the arithmetic mean of the thyroid dose over all subjects is estimated as 0.4 Gy, with individual values ranging from 1 mGy to 13 Gy. The uncertainties in the individual thyroid dose estimates, characterised by the geometric standard deviations of their probability distributions, range from 1.3 to 8.7, with an arithmetic mean of 3.2.