Total Synthesis of (±)-5-Deoxystrigol via Reductive Carbon-Carbon Bond Formation
Total Synthesis of (±)-5-Deoxystrigol via Reductive Carbon-Carbon Bond Formation
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DOI：
10.1021/jo9002085
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发表时间：
2009-05-15
影响因子：
3.6
通讯作者：
Ueda, Minoru
中科院分区：
文献类型：
--
作者：
Shoji, Mitsuru;Suzuki, Eriko;Ueda, Minoru
以炔烃的铝酸酯配合物与环氧化物之间的区域选择性偶联反应以及在过渡金属存在下的两次还原碳 - 碳键形成为关键步骤，成功实现了5 - 脱氧独脚金内酯的全合成。
The total synthesis of 5-deoxystrigol was successfully carried out via the regioselective coupling reaction between the aluminum ate complex of an alkyne and an epoxide and the two reductive carbon-carbon bond formations in the presence of transition metals as key steps.