Quantification of hemodynamic irregularity using oscillatory velocity index in the associations with the rupture status of cerebral aneurysms
Quantification of hemodynamic irregularity using oscillatory velocity index in the associations with the rupture status of cerebral aneurysms
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DOI：
10.1136/neurintsurg-2018-014489
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发表时间：
2019-06-01
影响因子：
4.8
通讯作者：
Suzuki, Hidenori
中科院分区：
文献类型：
--
作者：
Tanioka, Satoru;Ishida, Fujimaro;Suzuki, Hidenori
背景复杂和不稳定的血流模式被报道与脑动脉瘤的破裂状态有关，而它们的评估依赖于对血流流线的定性分析。振荡速度指数(OVI)是量化血流模式的血流动力学参数。本研究的目的是阐明OVI与脑动脉瘤破裂状态之间的关系。方法对129个破裂和未破裂的脑动脉瘤在脉动流动条件下进行计算流体力学分析。根据OVI的中位数将所有动脉瘤分为高OVI组和低OVI组。对两组的破裂情况、形态和血流动力学参数进行统计学分析。结果OVI值的中位数为0.006。破裂动脉瘤的OVI值较高(P=0.028)，并伴有不规则形状、复杂的血流模式和不稳定的血流模式(P
Background C omplex and unstable flow patterns are reported to be associated with the rupture status of cerebral aneurysms, while their evaluation depends on qualitative analysis of streamlines of bloodflow. Oscillatory velocity index (OVI) is a hemodynamic parameter to quantify flow patterns. The aim of this study is to elucidate the associations between OVI and the rupture status of cerebral aneurysms. Methods One hundred and twenty-nine ruptured and unruptured cerebral aneurysms were analyzed with computational fluid dynamics under pulsatile flow conditions. With the use of median value of OVI, all aneurysms were divided into high and low OVI groups. Statistical analysis was performed to compare rupture status, and morphological and hemodynamic parameters between the two groups. Results The median value of OVI was 0.006. High OVI was more likely observed in ruptured aneurysms (P= 0.028) and associated with irregular shape, complex flow patterns, and unstable flow patterns (P