Oncocytic mania: a review of oncocytic lesions throughout the body.
Oncocytic mania: a review of oncocytic lesions throughout the body.
复制标题
嗜酸细胞躁狂：对全身嗜酸细胞病变的回顾。
DOI：
10.1007/bf03347464
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发表时间：
2011
影响因子：
5.4
通讯作者：
Caturegli,P
中科院分区：
文献类型：
--
作者：
Guaraldi,F;Zang,G;Dackiw,AP;Caturegli,P
嗜酸细胞病变的病理特征是大量的嗜酸细胞，即增大的嗜酸性细胞和富含线粒体的细颗粒细胞。它们可以出现在许多器官和组织中，通常在内分泌腺中，并且与增生、自身免疫和肿瘤有关。将正常细胞转化为肿瘤细胞的原因和机制仍有待阐明。本文旨在回顾最常见的嗜酸细胞病变，强调其主要病理特征和临床意义。
Oncocytic lesions are characterized pathologically by an abundance of oncocytes, that is by enlarged, eosinophilic, and finely granular cells enriched in mitochondria. They can arise in numerous organs and tissues, often in endocrine glands, and have been associated with hyperplasia, autoimmunity, and neoplasia. The causes and mechanisms that transform a normal cell into an oncocyte remain to be elucidated. Aim of this article is to review the most common oncocytic lesions, highlighting their key pathological features and clinical significance.