Brief chemotherapy (Stanford V) and adjuvant radiotherapy for bulky or advanced Hodgkin's disease: an update.
Brief chemotherapy (Stanford V) and adjuvant radiotherapy for bulky or advanced Hodgkin's disease: an update.
复制标题
短期化疗(斯坦福 V)和辅助放疗治疗大块或晚期霍奇金病:更新。
DOI:
10.1093/annonc/7.suppl_4.s105
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发表时间:
1996
期刊:
影响因子:
--
通讯作者:
Hoppe,RT
中科院分区:
文献类型:
--
作者:
Horning,SJ;Rosenberg,SA;Hoppe,RT
From May 1989 to August 1995, 94 previously untreated patients with Hodgkin's disease stage II with bulky mediastinal involvement (n= 28) or stage III or IV (n= 66) received an abbreviated chemotherapy regimen, Stanford V, ± radiotherapy (RT). Chemotherapy was given weekly for 12 weeks followed by consolidative RT to sites of initial bulky disease. With a median follow-up of 3 years, the actuarial 6-year survival is 93% and the freedom from progression is 89%. There have been no relapses or deaths among the 28 patients with stage II bulky mediastinal disease. Eight relapses and three deaths have occurred in the group of 66 patients with stage III–IV disease. The abbreviated chemotherapy regimen, Stanford V, in combination with RT is well tolerated and highly effective therapy for bulky, limited stage and advanced stage HD. Lower cumulative exposure to alkylating agents, doxorubicin, bleomycin and limited use of radiation is expected to improve the prospects for fertility and decrease the risks for second neoplasms and late cardiopulmonary toxicity.
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DOI:
--
发表时间:
1993
期刊:
International Journal of Radiation Oncology, Biology, Physics
影响因子:
--
作者:
J. Earle
通讯作者:
J. Earle
影响因子:
1.2
作者:
J. Lagrange;A. Thyss;C. Caldani;M. Héry;M. Schneider;J. Bensadoun
通讯作者:
J. Bensadoun
影响因子:
20.3
作者:
Richard T. Hoppe;C. Coleman;Richard;Cox;Saul A. Rosenberg;Henry S. Kaplan
通讯作者:
Henry S. Kaplan
影响因子:
45.3
作者:
LONGO, DL;RUSSO, A;DEVITA, VT
通讯作者:
DEVITA, VT
DOI:
10.1001/jama.1993.03510160067031
发表时间:
1993-10
期刊:
JAMA
影响因子:
--
作者:
S. Hancock;M. Tucker;R. Hoppe
通讯作者:
S. Hancock;M. Tucker;R. Hoppe