Detection of brain metastasis at 3T: comparison among SE, IR-FSE and 3D-GRE sequences
Detection of brain metastasis at 3T: comparison among SE, IR-FSE and 3D-GRE sequences
复制标题
DOI：
10.1007/s00330-007-0599-9
复制
发表时间：
2007-09-01
影响因子：
5.9
通讯作者：
Kitajima, Mika
中科院分区：
文献类型：
--
作者：
Kakeda, Shingo;Korogi, Yukunori;Kitajima, Mika
本研究的目的是比较三种对比增强序列，自旋回波（SE）序列，反转恢复快速SE（IR-FSE）序列（均具有6 mm的切片厚度）和三维快速扰相梯度回波（3D快速SPGR）序列与1.4 mm各向同性体素在3 T下对脑转移瘤的检出能力。首先，进行体模研究，以量化对比增强比（CER）与三个序列。在21例连续脑转移瘤患者中，给予钆特醇后获得了3个序列的3 T轴向图像。两名神经放射学家评估了三种序列的脑转移瘤的可检测性。在体模研究中，三种序列的CER无明显差异。3D快速SPGR检测到的脑转移瘤明显多于SE和IR-FSE（3D快速SPGR共97个病灶，SE为64个，IR-FSE为63个）。特别是，3D快速SPGR在检测小病变方面上级其他两种序列（
The objective of this study is to compare the detectability of brain metastases at 3T among three contrast-enhanced sequences, spin-echo (SE) sequence, inversion recovery fast SE (IR-FSE) sequence (both with section thickness of 6 mm), and three-dimensional fast spoiled gradient-echo (3D fast SPGR) sequence with 1.4 mm isotropic voxel. First, phantom studies were performed to quantify the contrast-enhancement ratio (CER) with three sequences. In 21 consecutive patients with brain metastases, axial images of three sequences at 3T were obtained after administration of gadoteridol. Two neuroradiologists assessed the detectability of brain metastases for the three sequences. In the phantom study, no evident difference in the CER was demonstrated among three sequences. Significantly more brain metastases were detected with 3D fast SPGR than with SE and IR-FSE (a total of 97 lesions with 3D fast SPGR vs. 64 with SE and 63 with IR-FSE). In particular, 3D fast SPGR was superior to the other two sequences in detection of the small lesions (