Identifying protein domains with the Pfam database.
Identifying protein domains with the Pfam database.
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DOI：
10.1002/0471250953.bi0205s23
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发表时间：
2008-09-01
影响因子：
--
通讯作者：
Bateman, Alex
中科院分区：
文献类型：
--
作者：
Coggill, Penny;Finn, Robert D;Bateman, Alex
PFAM是蛋白质结构域家族的数据库，每个家族由多个序列比对和轮廓隐马尔可夫模型(HMM)表示。此外，每个族都有关联的注释、文献参考和指向其他数据库的链接。Pfam中的条目可通过万维网和平面文件格式获得。本单元包含有关如何访问和利用PFAM数据库中存在的信息的详细信息，即族、多条路线和注释。详细介绍了如何在远程和本地运行PFAM。
Pfam is a database of protein domain families, with each family represented by multiple sequence alignments and profile hidden Markov models (HMMs). In addition, each family has associated annotation, literature references, and links to other databases. The entries in Pfam are available via the World Wide Web and in flatfile format. This unit contains detailed information on how to access and utilize the information present in the Pfam database, namely the families, multiple alignments, and annotation. Details on running Pfam, both remotely and locally are presented.