Sphingosine kinase 1 is critically involved in nitric oxide‐mediated human endothelial cell migration and tube formation
Sphingosine kinase 1 is critically involved in nitric oxide‐mediated human endothelial cell migration and tube formation
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DOI：
10.1111/j.1476-5381.2010.00818.x
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发表时间：
2010-08
影响因子：
7.3
通讯作者：
S. Schwalm;J. Pfeilschifter;A. Huwiler
中科院分区：
文献类型：
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作者：
S. Schwalm;J. Pfeilschifter;A. Huwiler
背景和目的：鞘氨醇激酶（SK）将鞘氨醇转化为1-磷酸鞘氨醇（S1 P），后者是一种生物活性脂质，可调节多种细胞过程，包括增殖、分化和迁移。
Background and purpose: Sphingosine kinases (SKs) convert sphingosine to sphingosine 1‐phosphate (S1P), which is a bioactive lipid that regulates a variety of cellular processes including proliferation, differentiation and migration.