A comparison of pain report and adequacy of analgesic therapy in ambulatory - AIDS patients with and without a history of substance abuse

A comparison of pain report and adequacy of analgesic therapy in ambulatory - AIDS patients with and without a history of substance abuse
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DOI:
10.1016/s0304-3959(97)00039-0
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发表时间:
1997-08-01
期刊:
影响因子:
7.4
通讯作者:
Stein, K
Stein, K
中科院分区:
医学1区
文献类型:
--
作者:
Breitbart, W;Rosenfeld, B;Stein, K

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人们经常对患者疼痛报告的可信度表示担忧,这种担忧在艾滋病患者中尤为严重,因为许多患者有注射吸毒史。本研究比较了以注射吸毒 (IDU) 史作为 HIV 传播危险因素的艾滋病患者和有其他 HIV 传播危险因素的患者的疼痛经历、疼痛管理的充分性和心理健康状况。参与生活质量研究的 516 名流动艾滋病患者完成了一系列自我报告工具,包括简短疼痛量表、贝克抑郁量表、简短症状量表、功能生活量表和社会支持问卷。结果表明,注射吸毒者和非注射吸毒者受试者在疼痛发生率、疼痛强度或疼痛相关功能干扰方面没有显着差异。然而,IDU 患者接受镇痛药物不足的可能性明显更大,报告的疼痛缓解程度较低,心理困扰程度较高。在承认继续吸毒的患者、否认近期吸毒的患者以及参加美沙酮维持计划的患者中,疼痛强度、疼痛缓解或功能干扰的报告也没有差异。这些数据支持了艾滋病患者疼痛报告的有效性,至少在研究环境中是这样,并且表明疼痛治疗不足并不局限于主动滥用药物的患者。 (C) 1997 年国际疼痛研究协会。由 Elsevier Science B.V. 出版
Concerns are often raised regarding the credibility of patients' report of pain and this concern is heightened among individuals with AIDS, where many patients have a history of injection drug use. This study compared the pain experience, adequacy of pain management and psychological well-being among patients with AIDS who reported a history of injection drug use (IDU) as their HIV transmission risk factor and patients with other HIV transmission risk factors. Five hundred and sixteen ambulatory AIDS patients participating in a quality of life study completed a series of self-report instruments including the Brief Pain Inventory, the Beck Depression Inventory, the Brief Symptom Inventory, the Functional Living Inventory and the Social Support Questionnaire. Results demonstrated that IDU and non-IDU subjects did not differ significantly in their report of pain prevalence, pain intensity or pain-related functional interference. However, IDU patients were significantly more likely to receive inadequate analgesic medications, reported lower levels of pain relief and a greater degree of psychological distress. There was also no difference in report of pain intensity, pain relief or functional interference among patients who acknowledged continued drug use, those who denied any recent drug use and patients participating in a methadone maintenance program. These data support the validity of AIDS patients' report of pain, at least in research settings, and suggest that undertreatment of pain is not restricted to patients who actively abuse drugs. (C) 1997 International Association for the Study of Pain. Published by Elsevier Science B.V.