Quantitative phase imaging with partially coherent illumination
Quantitative phase imaging with partially coherent illumination
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DOI：
10.1364/ol.39.005511
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发表时间：
2014-10-01
期刊：
影响因子：
3.6
通讯作者：
Popescu, G.
中科院分区：
文献类型：
--
作者：
Nguyen, T. H.;Edwards, C.;Popescu, G.
在这封信中，我们建立了一个数学模型，用于预测定量相位成像(QPI)中当照明场部分空间相干时的实验结果。我们推导了适用于QPI的公式，并讨论了两类QPI实验的预期结果：公共路径和传统干涉测量，在不同的空间相干性程度下。特别是，我们的结果描述了照明场的空间相干性和光晕效应之间的物理关系，这在相差显微镜中是众所周知的。我们进行了与这种常见情况相关的实验，发现我们的理论与数据非常吻合。通过对空间相干性影响的新理解，我们的公式提供了一种从相位图像中去除晕状伪影的途径。(C)2014年美国光学学会
In this Letter, we formulate a mathematical model for predicting experimental outcomes in quantitative phase imaging (QPI) when the illumination field is partially spatially coherent. We derive formulae that apply to QPI and discuss expected results for two classes of QPI experiments: common path and traditional interferometry, under varying degrees of spatial coherence. In particular, our results describe the physical relationship between the spatial coherence of the illuminating field and the halo effect, which is well known in phase-contrast microscopy. We performed experiments relevant to this common situation and found that our theory is in excellent agreement with the data. With this new understanding of the effects of spatial coherence, our formulae offer an avenue for removing halo artifacts from phase images. (C) 2014 Optical Society of America