Dynamic removal of oral biofilms by bubbles.
Dynamic removal of oral biofilms by bubbles.
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通过气泡动态去除口腔生物膜。
DOI：
10.1016/j.colsurfb.2006.06.005
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发表时间：
2006
期刊：
影响因子：
--
通讯作者：
Pitt,WilliamG
中科院分区：
文献类型：
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作者：
Parini,MichaelR;Pitt,WilliamG
从固体表面去除生物膜的一种新方法是使大量气泡通过表面。当用某些类型的电动牙刷刷牙时，会发生这种现象，电动牙刷会加速气泡流体抵靠或穿过牙齿表面。视频记录的气泡推动对成熟的生物膜的变形链球菌显示，气泡消除生物膜在碰撞点。提出了去除过程的数学模型，并能够模拟生物膜去除过程的动力学。去除速率被建模为与气泡足迹面积和每次碰撞次数成比例。每次气泡碰撞去除的生物膜的分数大约为0.4，该值比基于先前的研究所预期的值大得多，所述研究采用沿着沿着部分被粘附细菌覆盖的表面缓慢移动的气泡。更高的去除效率归因于流体动力学剪切力，该剪切力与当气泡接触生物膜时从表面拉动细菌的热力学力一起发生。预期快速气泡流可从诸如牙齿的硬表面去除细菌生物膜。
A novel approach to the removal of biofilms from solid surfaces is to pass large numbers of air bubbles over the surfaces. Such a phenomenon occurs when teeth are brushed with some types of powered toothbrushes that accelerate bubbly fluid against or across teeth surfaces. Video recordings of air bubbles propelled against a mature biofilm of Streptococcus mutans showed that the bubbles removed the biofilm at the point of collision. A mathematical model of the removal process was proposed and was able to simulate the kinetics of the biofilm removal process. Removal rate was modeled to be proportional to the bubble footprint area and the number of collisions per time. The fraction of biofilm removed per bubble collision is on the order of 0.4, a value much larger than would have been expected based on previous research employing bubbles that moved slowly along a surface that was partially covered with adherent bacteria. The higher removal efficiency is attributed to fluid dynamic shear forces that occur in conjunction with the thermodynamic forces that pull bacteria from a surface as a bubble contacts the biofilm. Fast bubbly flow is expected to remove bacterial biofilm from hard surfaces such as teeth.