Quantitative evaluation of the impact of active efflux by P-gp and Bcrp at the BBB on the predictability of the unbound concentrations of drugs in the brain using cerebrospinal fluid concentration as surrogate
Quantitative evaluation of the impact of active efflux by P-gp and Bcrp at the BBB on the predictability of the unbound concentrations of drugs in the brain using cerebrospinal fluid concentration as surrogate
复制标题
使用脑脊液浓度作为替代，定量评估 BBB 处 P-gp 和 Bcrp 的主动流出对大脑中未结合药物浓度的可预测性的影响
DOI：
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复制
发表时间：
2011
期刊：
影响因子：
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通讯作者：
and Yuichi Sugiyama
中科院分区：
文献类型：
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作者：
Hiroshi Kodaira;Hiroyuki Kusuhara;Takuya Fujita;Junko Ushiki;Eiichi Fuse;and Yuichi Sugiyama
