Novel Fluorescent Probes for Singlet Oxygen.
Novel Fluorescent Probes for Singlet Oxygen.
复制标题
DOI：
10.1002/(sici)1521-3773(19991004)38:19
复制
发表时间：
1999-10
影响因子：
--
通讯作者：
N. Umezawa;Kumi Tanaka;Y. Urano;K. Kikuchi;T. Higuchi;T. Nagano
中科院分区：
文献类型：
--
作者：
N. Umezawa;Kumi Tanaka;Y. Urano;K. Kikuchi;T. Higuchi;T. Nagano
第一个荧光化学陷阱（1）O（2）已经开发出来。DPAX与（1）O（2）发生特异性反应，生成相应的内过氧化物DPAX-EP（见方案; X = H、Cl、F）。DPAX几乎不发荧光，而DPAX-EP发强荧光。由于这些探针的荧光不受H（2）O（2）、超氧化物和一氧化氮的影响，因此它们可用于生物系统中（1）O（2）的选择性检测。
The first fluorescent chemical traps for (1)O(2) have been developed. DPAXs react specifically with (1)O(2) to yield the corresponding endoperoxides, DPAX-EPs (see scheme; X = H, Cl, F). DPAXs scarcely fluoresce, while DPAX-EPs are strongly fluorescent. Since the fluorescence of these probes is unaffected by H(2)O(2), superoxide, and nitric oxide, they are useful for the selective detection of (1)O(2) in biological systems.