REGULATION OF THE ESCHERICHIA-COLI HFQ GENE ENCODING THE HOST FACTOR FOR PHAGE Q-BETA
REGULATION OF THE ESCHERICHIA-COLI HFQ GENE ENCODING THE HOST FACTOR FOR PHAGE Q-BETA
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DOI：
10.1128/jb.176.2.531-534.1994
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发表时间：
1994-01-01
影响因子：
3.2
通讯作者：
ISHIHAMA, A
中科院分区：
文献类型：
--
作者：
KAJITANI, M;KATO, A;ISHIHAMA, A
噬菌体Q(β) RNA复制的宿主因子(HF-I)是一种由102个氨基酸残基组成的小蛋白质，由大肠杆菌染色体上94.8分钟的hfq基因编码。指数生长期的HF-I合成率高于稳定期，并且随着细胞生长率的增加而增加。 HF-1的细胞内水平为每个细胞约30,000至60,000个分子，其中大部分与作为盐洗蛋白之一的核糖体相关。综上所述，我们认为 HF-I 是生长相关蛋白之一。
The host factor (HF-I) for phage Q(beta) RNA replication is a small protein of 102 amino acid residues encoded by the hfq gene at 94.8 min on the Escherichia coli chromosome. The synthesis rate of HF-I at the exponential-growth phase is higher than at the stationary phase, and it increases concomitantly with the increase in cell growth rate. The intracellular level of HF-I is about 30,000 to 60,000 molecules per cell, the majority being associated with ribosomes as one of the salt wash proteins. Taken together, we suggest that HF-I is one of the growth-related proteins.