Corrigendum: Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes.
Corrigendum: Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes.
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勘误表：1 型糖尿病人类捐献者胰岛浸润 T 细胞自身抗原特异性的分析。
DOI：
10.1038/nm0817-1004a
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发表时间：
2017
期刊：
影响因子：
82.9
通讯作者：
Mathieu,Chanta
中科院分区：
文献类型：
--
作者：
Babon,JennyAurielleB;DeNicola,MeganE;Blodgett,DavidM;Crèvecoeur,Inne;Buttrick,ThomasS;Maehr,René;Bottino,Rita;Naji,Ali;Kaddis,John;Elyaman,Wassim;James,EddieA;Haliyur,Rachana;Brissova,Marcela;Overbergh,Lut;Mathieu,Chanta
在本文最初发表的版本中，被识别为 T 细胞克隆靶标的 IA-2545-562 肽被错误标记为该肽的天然版本。 T 细胞克隆对在位置 548、551 和 556 处具有谷氨酰胺到谷氨酸脱氨基的肽的修饰版本做出反应。句子，“来自供体 T1D.7，CD4+ T 细胞克隆识别出具有三个谷氨酰胺到谷氨酸脱氨基的 IA-2 肽 (IA-2545–562 (Q–G548, 551,556)；图 2e)”已添加到第 12 页。第1484章 反映这一点。相关文本也已在第 14 页的正文中进行了编辑。第1483章在图2e和图2图例中；以及图 3b 中。此外，短语“脱氨基 IA-2 肽”已添加到在线方法的“肽”部分的“...（一组 60 种肽）...”之后。最后，在图 2 图例中，短语“检测已知自身反应目标的反应性...”已更改为“检测对自身反应目标的反应性...”。这些错误已在文章的 HTML 和 PDF 版本中得到纠正。
In the version of this article initially published, the IA-2545–562 peptide identified as a target of a T cell clone was mislabeled as the native version of the peptide. The T cell clone responded to a modified version of the peptide with glutamine-to-glutamic-acid deaminations at positions 548, 551 and 556. The sentence,“From donor T1D. 7, a CD4+ T cell clone recognized an IA-2 peptide with three glutamine-to-glutamic-acid deaminations (IA-2545–562 (Q–G548, 551,556); Fig. 2e)” has been added on p. 1484 to reflect this. The relevant text has also been edited in the main text on p. 1483; in Figure 2e and the Figure 2 legend; and in Figure 3b. Additionally, the phrase,‘, a deaminated IA-2 peptide’has been added after ‘…(a panel of 60 peptides)…’to the ‘Peptides’ section of the Online Methods. Finally, in the Figure 2 legend, the phrase ‘Detection of reactivity to known autoreactive targets…’has been changed to ‘Detection of reactivity to autoreactive targets…’. These errors have been corrected in the HTML and PDF versions of the article.