Topography of the human corpus callosum using diffusion tensor tractography
Topography of the human corpus callosum using diffusion tensor tractography
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DOI：
10.1097/00004728-200407000-00016
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发表时间：
2004-07-01
影响因子：
1.3
通讯作者：
Ohtomo, K
中科院分区：
文献类型：
--
作者：
Abe, O;Masutani, Y;Ohtomo, K
目的：为了评估通过胼胝体使用失真校正的扩散张量纤维束成像在人脑中的交叉纤维轨迹。方法：在校正与大扩散梯度相关的失真后，从10名右利手健康男性获得的T2加权回波平面图像（EPI）被配准到T2加权快速自旋回波图像，使用线性到六阶非线性，3维，多项式翘曲函数。最佳的转换参数也被应用到失真校正的扩散加权EPI。结果：经胼胝体的磁共振弥散张量纤维束成像与经眶额部的磁共振弥散张量纤维束成像相比，经喙部的磁共振弥散张量纤维束成像走行更靠后，似乎进入了眶回。这些线进入后颞部白色物质（绒毡层）穿过压部的腹侧部分，并明确区分线，达到顶枕部白色物质（钳major.Conclusion：扩散张量纤维束成像是一种可行的无创工具，以评估连合纤维轨迹。
Objective: To evaluate the crossing fiber trajectory through the corpus callosum using distortion-corrected diffusion tensor tractography in the human brain.Methods: After correcting distortion associated with large-diffusion gradients, T2-weighted echo planar images (EPIs) acquired from 10 right-handed healthy men were coregistered into T2-weighted fast spin echo images using linear through sixth-order nonlinear, 3-dimensional, polynomial warping functions. The optimal transformation parameters were also applied to the distortion-corrected diffusion-weighted EPIs. Diffusion tensor tractography through the corpus callosum was reconstructed, employing the "1 or 2 regions of interest" method.Results: Compared with the lines through the genu, those through the rostrum ran more inferiorly and seemed to enter the orbital gyrus. Those lines entering posterior temporal white matter (tapetum) crossed through the ventral portion of the splenium and were clearly distinguished from lines that reached parieto-occipital white matter (forceps major).Conclusion: Diffusion tensor tractography is a feasible noninvasive tool to evaluate commissural fiber trajectory.