A SEROLOGICAL STUDY OF CELL FRACTIONS DURING EMBRYONIC DEVELOPMENT OF LIVER IN CHICK
A SEROLOGICAL STUDY OF CELL FRACTIONS DURING EMBRYONIC DEVELOPMENT OF LIVER IN CHICK
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DOI：
10.1016/0014-4827(63)90397-5
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发表时间：
1963-01-01
影响因子：
3.7
通讯作者：
PIAZZA, E
中科院分区：
文献类型：
--
作者：
DAMELIO, V;MUTOLO, V;PIAZZA, E
用免疫学方法研究了鸡肝发育过程中的亚细胞组分。9日龄胚胎的线粒体组分表现出与成人肝脏制备的线粒体组分相同的反应模式。从胚胎肝脏制备的微粒体和细胞液组分在发育过程中获得一些成人型抗原。在发育的最早阶段，一些成体微粒体的典型抗原（被证明与RNP颗粒结合）明显缺乏。胚胎微粒体组分显示出比成体微粒体更高的RNA/蛋白质N比，直到发育的第18天，此时该比变为成体类型。
The subcellular fractions of the developing chick liver have been studied by immunological methods. The mitochondrial fraction from 9 day old embryos exhibits the reaction pattern as the one prepared from the adult liver. The microsomal and the cell sap fractions prepared from embryonic liver acquire some adult type antigens during the course of development. In the earliest stages of development some of the antigens typical of the adult microsomes (proved to be bound to the RNP particles) are apparently lacking. The embryonic microsomal fraction shows a higher RNA/ protein N ratio than that of the adult microsomes until the 18th day of development, when the ratio becomes of the adult type.