New Decade of Vaccines 4 The future of immunisation policy, implementation, and financing
New Decade of Vaccines 4 The future of immunisation policy, implementation, and financing
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DOI：
10.1016/s0140-6736(11)60406-6
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发表时间：
2011-07-01
期刊：
影响因子：
168.9
通讯作者：
Greenwood, Brian
中科院分区：
文献类型：
--
作者：
Levine, Orin S.;Bloom, David E.;Greenwood, Brian
疫苗已经挽救了许多人的生命，而且随着越来越复杂的技术提供新的有效疫苗，可以预防目前没有有效许可疫苗的传染病，如疟疾、结核病和艾滋病毒，以及非传染性疾病，如高血压和糖尿病，疫苗有可能挽救更多人的生命。然而，这些新疫苗可能比过去有效使用的疫苗更加复杂和昂贵，并且它们可能对它们旨在预防的疾病产生多方面的影响，正如肺炎球菌结合疫苗所看到的那样。决定一个国家应该投资哪种新疫苗不仅需要世卫组织等国际组织的合理建议，还需要一个信息灵通的国家免疫咨询委员会，该委员会可以获得当地疾病负担的适当数据。引进疫苗可能需要修改免疫接种时间表和接种程序。需要新的方法来资助越来越多的新疫苗，这些疫苗有可能在太穷而负担不起的国家拯救生命。在这里，我们讨论一些选择。
Vaccines have already saved many lives and they have the potential to save many more as increasingly elaborate technologies deliver new and effective vaccines against both infectious diseases for which there are currently no effective licensed vaccines such as malaria, tuberculosis, and HIV and non-infectious diseases such as hypertension and diabetes. However, these new vaccines are likely to be more complex and expensive than those that have been used so effectively in the past, and they could have a multifaceted effect on the disease that they are designed to prevent, as has already been seen with pneumococcal conjugate vaccines. Deciding which new vaccines a country should invest in requires not only sound advice from international organisations such as WHO but also a well informed national immunisation advisory committee with access to appropriate data for local disease burden. Introduction of vaccines might need modification of immunisation schedules and delivery procedures. Novel methods are needed to finance the increasing number of new vaccines that have the potential to save lives in countries that are too poor to afford them. Here, we discuss some options.