ELECTROPHYSIOLOGICAL TECHNIQUES IN AUDIOLOGY AND OTOLOGY - COCHLEAR SUMMATING POTENTIAL TO BROAD-BAND CLICKS DETECTED FROM THE HUMAN EXTERNAL AUDITORY MEATUS - A STUDY OF SUBJECTS WITH NORMAL HEARING FOR AGE
ELECTROPHYSIOLOGICAL TECHNIQUES IN AUDIOLOGY AND OTOLOGY - COCHLEAR SUMMATING POTENTIAL TO BROAD-BAND CLICKS DETECTED FROM THE HUMAN EXTERNAL AUDITORY MEATUS - A STUDY OF SUBJECTS WITH NORMAL HEARING FOR AGE
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DOI：
10.1097/00003446-198505000-00002
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发表时间：
1985-01-01
期刊：
影响因子：
3.7
通讯作者：
SNYDER, JM
中科院分区：
文献类型：
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作者：
CHATRIAN, GE;WIRCH, AL;SNYDER, JM
用无创电极从外耳道（EAM）记录听神经复合动作电位（AP）前的耳蜗总和电位（SP），年龄12 ~ 67岁。获得定量数据：显示可测量的SP的耳数; SP检测水平; SP发作、峰值和上升时间; SP-AP复合体的持续时间; SP振幅;和SP/AP振幅比。先前未知的关系之间的振幅，但不是时间，SP和偏侧性，性别，年龄和听力测定确定的听力阈值4至8 kHz的音调的措施被揭开。最高的相关性与这些最后的阈值，这表明，在耳蜗的基底回的受体在EAM检测到的SP的产生中发挥了主导作用。为了改善现有的技术，用于确定异常SP升高，设计了一种多元回归方法，利用性别，年龄，4至8 kHz的听力阈值，和AP电压来建立个体受试者和耳朵的SP振幅的正常上限。
The cochlear summating potential (SP) preceding the auditory nerve compound action potential (AP) was elicited by broadband alternating condensation and rarefaction clicks and recorded by noninvasive electrodes from the external auditory meatus (EAM) of 60 volunteers of both sexes, 12 to 67 years old, who had normal hearing for age. Quantitative data were obtained on: the number of ears displaying measurable SPs; the SP detection level; the SP onset, peak and rise times; the duration of the SP-AP complex; the SP amplitude; and the SP/AP amplitude ratio. Previously unknown relationships were unveiled between the amplitude, but not the temporal, measures of the SP and laterality, sex, age, and audiometrically determined hearing thresholds to 4 to 8 kHz tones. The highest correlations were obtained with these last thresholds, which suggested that receptors in the basal turn of the cochlea played a dominant role in the generation of the EAM-detected SP. To improve on existing techniques for determining abnormal SP elevation, a multiple regression method was devised that utilized sex, age, 4 to 8 kHz hearing thresholds, and AP voltage to establish upper normal limits of SP amplitude for individual subjects and ears.