Psychometrics of the PHQ-9 as a measure of depressive symptoms in patients with heart failure

Psychometrics of the PHQ-9 as a measure of depressive symptoms in patients with heart failure
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DOI:
10.1177/1474515112468068
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发表时间:
2013-10-01
影响因子:
2.9
通讯作者:
Moser, Debra K.
Moser, Debra K.
中科院分区:
医学2区
文献类型:
--
作者:
Hammash, Muna H.;Hall, Lynne A.;Moser, Debra K.

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背景心力衰竭患者的抑郁症通常未被诊断和治疗。患者健康问卷-9(PHQ-9)是一种简单有效的抑郁症状测量方法,可促进临床评估。目的检验PHQ-9量表在心力衰竭患者中的信度、同时效度和结构效度(32%女性,61 ± 12岁,56%纽约心脏协会III/IV级)完成了PHQ-9、贝克抑郁量表-II(BDI-II),结果本样本的Cronbach’s alpha值为.83,支持PHQ-9的内部一致性信度。项目间相关(范围.22-.66)和项目-总相关(项目9除外)支持PHQ-9的同质性。PHQ-9和BDI-II之间的斯皮尔曼rho为0.80(p <0.001),支持PHQ-9和BDI-II之间的一致性(Kappa = 0.64,p <0.001)。在截止分数为10时,PHQ-9在识别抑郁症状方面的敏感性为70%,特异性为92%,使用BDI-II评分作为比较标准。PHQ-9评分与CAS测量的控制感水平之间的差异(t(318)=-5.05,p < .001)支持结构效度。结论PHQ-9是一种可靠、有效的心力衰竭患者抑郁症状的测量方法。
Background Depression in patients with heart failure commonly goes undiagnosed and untreated. The Patient Health Questionnaire-9 (PHQ-9) is a simple, valid measure of depressive symptoms that may facilitate clinical assessment. It has not been validated in patients with heart failure.Aims To test the reliability, and concurrent and construct validity of the PHQ-9 in patients with heart failure.Methods A total of 322 heart failure patients (32% female, 61 12 years, 56% New York Heart Association class III/IV) completed the PHQ-9, the Beck Depression Inventory-II (BDI-II), and the Control Attitudes Scale (CAS).Results Cronbach's alpha of .83 supported the internal consistency reliability of the PHQ-9 in this sample. Inter-item correlations (range .22-.66) and item-total correlation (except item 9) supported homogeneity of the PHQ-9. Spearman's rho of .80, (p < .001) between the PHQ-9 and the BDI-II supported the concurrent validity as did the agreement between the PHQ-9 and the BDI-II (Kappa = 0.64, p < .001). At cut-off score of 10, the PHQ-9 was 70% sensitive and 92% specific in identifying depressive symptoms, using the BDI-II scores as the criterion for comparison. Differences in PHQ-9 scores by level of perceived control measured by CAS (t(318) = -5.05, p < .001) supported construct validity.Conclusion The PHQ-9 is a reliable, valid measure of depressive symptoms in patients with heart failure.