OUTCOME AFTER STEREOTAXIC THALAMOTOMY FOR DYSTONIA AND HEMIBALLISMUS
OUTCOME AFTER STEREOTAXIC THALAMOTOMY FOR DYSTONIA AND HEMIBALLISMUS
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DOI：
10.1227/00006123-199503000-00009
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发表时间：
1995-03-01
期刊：
影响因子：
4.8
通讯作者：
HAMILTON, WJ
中科院分区：
文献类型：
--
作者：
CARDOSO, F;JANKOVIC, J;HAMILTON, WJ
本文回顾了17例肌张力障碍和2例偏侧震颤患者接受单次或分期立体定向丘脑切开术后的结果。尽管进行了最佳的药物治疗，但所有患者均因运动障碍而严重残疾。8例肌张力障碍患者（47%）在手术后立即出现中度改善。在随访期间（平均37.6个月），这8例患者中有6例保持了改善，另外2例肌张力障碍患者显著改善。继发性肌张力障碍患者的长期结局（平均41.0个月时50%中度或显著改善）优于原发性肌张力障碍患者（平均32.9个月时43%中度或显著改善）。在接受丘脑切开术治疗偏侧震颤的两例患者中均获得了良好的控制。
THE OUTCOME AFTER single or staged stereotactic thalamotomies in 17 patients with dystonia and 2 patients with hemiballismus is reviewed. All patients were severely disabled by their movement disorders despite optimal pharmacological therapies. Eight of the patients with dystonia (47%) showed moderate improvement immediately after the procedures. Six of these eight patients maintained their improvement, and two other patients with dystonia improved significantly, during the follow-up period (mean, 37.6 mo). The long-term outcome was better in patients with secondary dystonia (50% moderately or markedly improved at a mean of 41.0 mo) than in patients with primary dystonia (43% moderately or markedly improved at a mean of 32.9 mo). Excellent control was achieved in both of the patients who underwent thalamotomies for hemiballismus.