Application of magnetic particles in forensic science
Application of magnetic particles in forensic science
复制标题
磁性粒子在法医学中的应用
DOI：
10.1016/j.trac.2019.115674
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发表时间：
2019
影响因子：
13.1
通讯作者：
Huang Chuixiu
中科院分区：
文献类型：
--
作者：
Liu Cong;Wu Shifan;Yan Yibo;Dong Ying;Shen Xiantao;Huang Chuixiu
随着刑事侦查对准确、灵敏诊断的要求越来越高，磁颗粒以其独特的性质在法医学领域受到越来越多的关注。这篇重要的综述简要总结了提高MPs特异性的方法，并强调了它们最近在法医学中的应用。在介绍磁固相萃取技术的基础上，综述了磁固相萃取技术在小分子毒物提取中的研究进展。此外，MSPE还可用于生物分子（包括高质量DNA、蛋白质和细胞）的个体鉴定或公共安全。此外，还综述了MPs在提供高质量的潜在指纹图像和沉积在潜在指纹图像中的关键化学信息方面的研究机会。探讨了法医学多功能MPs的研究方向，提出了构建多功能MPs的研究方向。
With the increasing demand of accurate and sensitive diagnosis for criminal investigation, magnetic particles (MPs) have attracted more and more attentions in forensic science due to their unique properties. This critical review briefly summarized the methodology to enhance the specificity of MPs and highlighted their recent applications in forensic science. After an introduction of MPs, we first summarized the recent developments of magnetic solid-phase extraction (MSPE) of small molecular poisons. Moreover, MSPE of biomolecules including high quality DNA, proteins and cells for individual identification or public security was highlighted. In addition, research opportunities in providing high-quality images of latent fingerprints (LFPs) and critical chemical information deposited in the LFPs by MPs were also reviewed. The challenges of the MPs were also addressed to define the research direction of creating multifunctional MPs in forensic science.