Emerging infectious pathogens of wildlife
Emerging infectious pathogens of wildlife
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DOI：
10.1098/rstb.2001.0900
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发表时间：
2001-07-29
影响因子：
6.3
通讯作者：
Foufopoulos, J
中科院分区：
文献类型：
--
作者：
Dobson, A;Foufopoulos, J
本文第一部分调查了ProMED网站1998 - 2000年间记录的野生动物新发病原体。在野生动物中引起疾病暴发的大多数病原体在起源上都是病毒。在绝大多数病例中，人为活动引起了疫情。本文第二部分建立了一些矩阵模型，用于量化引起野生动物暴发的各种潜在突发病原体的基本繁殖数R-0。这些分析强调了R-0对寄主种群空间结构或病原体利用多种寄主物种的能力所产生的异质性的敏感性。在每个阶段，我们说明了该方法如何提供洞察紧急病原体的初始动态，如犬细小病毒，莱姆病和西尼罗河病毒在美国。
The first part of this paper surveys emerging pathogens of wildlife recorded on the ProMED Web site for a 2-year period between 1998 and 2000. The majority of pathogens recorded as causing disease outbreaks in wildlife were viral in origin. Anthropogenic activities caused the outbreaks in a significant majority of cases. The second part of the paper develops some matrix models for quantifying the basic reproductive number, R-0, for a variety of potential types of emergent pathogen that cause outbreaks in wildlife. These analyses emphasize the sensitivity of R-0, to heterogeneities created by either the spatial structure of the host population, or the ability of the pathogens to utilize multiple host species. At each stage we illustrate how the approach provides insight into the initial dynamics of emergent pathogens such as canine parvovirus, Lyme disease, and West Nile virus in the United States.