PARAQUAT POISONING: SIGNIFICANCE OF PLASMA-PARAQUAT CONCENTRATIONS

PARAQUAT POISONING: SIGNIFICANCE OF PLASMA-PARAQUAT CONCENTRATIONS
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DOI:
10.1016/s0140-6736(79)90345-3
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发表时间:
1979-08
期刊:
The Lancet
影响因子:
--
通讯作者:
A. Proudfoot;M. Stewart;T. Levitt;B. Widdop
A. Proudfoot;M. Stewart;T. Levitt;B. Widdop
中科院分区:
其他
文献类型:
--
作者:
A. Proudfoot;M. Stewart;T. Levitt;B. Widdop

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对79名服用含有百草枯的液体或颗粒状除草剂的患者进行了血浆百草枯浓度测定。在摄入后的任何给定时间,死亡患者的血浆百草枯浓度通常都超过幸存者。提示血浆百草枯浓度的测定对评估中毒的严重程度和预测结果有一定的参考价值。血药浓度在4、6、10、16、24 h分别不超过2.0、0.6、0.3、0.16和0.1 mg/L的患者有可能存活。
Plasma-paraquat concentrations were measured in 79 patients who had ingested liquid or granular weedkillers containing paraquat. At any given time after ingestion, the plasma-paraquat concentrations in the patients who died usually exceeded those in the survivors. It is suggested that measurement of plasma-paraquat concentrations is useful in assessing the severity and predicting the outcome of poisoning. Patients whose plasma concentrations do not exceed 2·0, 0·6, 0·3, 0·16, and 0·1 mg/l at 4, 6, 10, 16, and 24 h respectively are likely to survive.