Erythrocyte Velocity and a Velocity Pulse in Minute Blood Vessels on the Surface of the Mouse Brain

Erythrocyte Velocity and a Velocity Pulse in Minute Blood Vessels on the Surface of the Mouse Brain
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小鼠大脑表面微小血管中的红细胞速度和速度脉冲

DOI:
10.1161/01.res.24.6.887
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发表时间:
1969
影响因子:
20.1
通讯作者:
W. Rosenblum
W. Rosenblum
中科院分区:
医学1区
文献类型:
--
作者:
W. Rosenblum

文献摘要

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麻醉小鼠蛛网膜下腔血管高速显微摄影,测量直径小于30μ的小动脉和小静脉内红细胞的流速。在小动脉内,平均流速为3.5毫米/秒,而在小静脉中,平均流速为1.9毫米/秒。在小动脉中常观察到速度的节律性改变,在小静脉中偶见。这种速度的周期性变化被称为“速度脉冲”。速度脉冲的频率几乎与外周脉冲的频率相同,据信是由外周脉冲传播到微循环造成的。在5μ ~ 10μ宽的血管中,速度脉冲无法识别。在直径为10 ~ 30μ的血管中,流速脉冲不随血管宽度的变化而变化。
High-speed microcinematography of vessels in the subarachnoid space of the anesthetized mouse was used to measure the velocity of erythrocytes in arterioles and venules less than 30μ in diameter. Within arterioles the velocity averaged 3.5 mm/sec, while in venules an average value of 1.9 mm/sec was obtained. A rhythmic alteration in velocity was often observed in the arterioles and was seen occasionally in venules. This cyclical change in velocity was termed the “velocity pulse.” The frequency of the velocity pulse was virtually identical to that of the peripheral pulse and is believed to result from a propagation of that pulse into the microcirculation. The velocity pulse was not recognizable in vessels 5μ to 10μ wide. In vessels 10μ, to 30μ, in diameter, the velocity pulse was not accompanied by changes in the width of the vessels.