Trends in the Inactive Kidney Transplant Waitlist and Implications for Candidate Survival
Trends in the Inactive Kidney Transplant Waitlist and Implications for Candidate Survival
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DOI:
10.1111/ajt.12143
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发表时间:
2013-04-01
影响因子:
8.8
通讯作者:
Segev, D. L.
中科院分区:
文献类型:
--
作者:
Grams, M. E.;Massie, A. B.;Segev, D. L.
In November 2003, OPTN policy was amended to allow kidney transplant candidates to accrue waiting time while registered as status 7, or inactive. We evaluated trends in inactive listings and the association of inactive status with transplantation and survival, studying 262824 adult first-time KT candidates listed between 2000 and 2011. The proportion of waitlist candidates initially listed as inactive increased from 2.3% prepolicy change to 31.4% in 2011. Candidates initially listed as inactive were older, more often female, African American, and with higher body mass index. Postpolicy change, conversion from initially inactive to active status generally occurred early if at all: at 1 year after listing, 52.7% of initially inactive candidates had been activated; at 3 years, only 66.3% had been activated. Inactive status was associated with a substantially higher waitlist mortality (aHR 2.21, 95%CI:2.152.28, p